Vitamin D is relevant to several processes in the body mainly in the intracellular mechanisms affecting parathyroid hormone and calcitonin regulation, regulation of vitamin D production by negative feedback and calcium and phosphorous level regulation. Vitamin D may be synthesised in the dermal layer of the skin or absorbed through the diet and utilised. Its biosynthesis initiates from cholesterol and its derivatives and is followed by a cascade of reactions, completed in the kidneys and transported via the blood to where it is utilized. The vitamin D receptor determines the physiological effects of vitamin D and any mutations will cause imbalances in bone homeostasis.
Stephanie Galea and Renald Blundell. Physiology of Vitamin D.
DOI: https://doi.org/10.36478/ijmmas.2011.1.4
URL: https://www.makhillpublications.co/view-article/1813-176x/ijmmas.2011.1.4