Stephanie Galea, Renald Blundell, Physiology of Vitamin D, International Journal of Molecular Medicine and Advance Sciences, Volume 7,Issue 1, 2011, Pages 1-4, ISSN 1813-176x, ijmmas.2011.1.4, (https://makhillpublications.co/view-article.php?doi=ijmmas.2011.1.4) Abstract: Vitamin D is relevant to several processes in the body mainly in the intracellular mechanisms affecting parathyroid hormone and calcitonin regulation, regulation of vitamin D production by negative feedback and calcium and phosphorous level regulation. Vitamin D may be synthesised in the dermal layer of the skin or absorbed through the diet and utilised. Its biosynthesis initiates from cholesterol and its derivatives and is followed by a cascade of reactions, completed in the kidneys and transported via the blood to where it is utilized. The vitamin D receptor determines the physiological effects of vitamin D and any mutations will cause imbalances in bone homeostasis. Keywords: Dihydrocholecalciferol;vitamin D receptor;calcium;parathyroid hormone;phosphate;calcitonin