TY - JOUR T1 - Physiology of Vitamin D AU - Galea, Stephanie AU - Blundell, Renald JO - International Journal of Molecular Medicine and Advance Sciences VL - 7 IS - 1 SP - 1 EP - 4 PY - 2011 DA - 2001/08/19 SN - 1813-176x DO - ijmmas.2011.1.4 UR - https://makhillpublications.co/view-article.php?doi=ijmmas.2011.1.4 KW - Dihydrocholecalciferol KW -vitamin D receptor KW -calcium KW -parathyroid hormone KW -phosphate KW -calcitonin AB - Vitamin D is relevant to several processes in the body mainly in the intracellular mechanisms affecting parathyroid hormone and calcitonin regulation, regulation of vitamin D production by negative feedback and calcium and phosphorous level regulation. Vitamin D may be synthesised in the dermal layer of the skin or absorbed through the diet and utilised. Its biosynthesis initiates from cholesterol and its derivatives and is followed by a cascade of reactions, completed in the kidneys and transported via the blood to where it is utilized. The vitamin D receptor determines the physiological effects of vitamin D and any mutations will cause imbalances in bone homeostasis. ER -