Journal of Diabetes, Metabolism and Endocrinology
ISSN: Online 2708-2717ISSN: Print 2708-2709
Abstract
Glycated Hemoglobin (HbA1c) is now used largely for DM control. HbA1c is influenced by many risk factors; these include Body Mass Index (BMI), physical activity, age, ethnicity, diet, smoking and Blood Pressure (BP). Previous studies showed that the levels of HbA1c showed different relationship with physical activity and diet. The objective of this study is to investigate the physical activity and diets as determinants of glycated hemoglobin in non-diabetic Sudanese population. A cross sectional study was conducted during 2016-2018 in Sudan covering Khartoum state, Northern state, Gezira state, Red Sea state and North Darfur state, on adults of ages between 20-60 years and not known to be diabetic or suffering from any chronic illness. The 1096 participants were assessed by a questionnaire covering age, gender, dietary intake in the previous month, physical activity and other demographic and social characteristics. BMI and BP were calculated by standard scales. A sample of 5 mL venous blood was taken for FBG to exclude DM and measurement of HbA1c using a modified ELISA reader known as Cobas Integra 800 (Roch) machine. Correlations between the variables were estimated and p<0.05 was considered statistically significant. The overall mean value of HbA1c was 4.6%±0.9 with a minimum value of 1.2% and maximums of 6.3. At 95% confidence interval the lower bound Mean was 4.5% and the upper bound mean was 4.7%. The mean age of the participants was found to be 25.1±9.2 years with a range of 20-60 years. The mean of BMI was found to be 22.8±4.8 with a minimum of 18.5 and maximum of 51.4. 497(45.3%) of the participants were physically active. The physical activity level negatively affected HbA1c (p = 0.004). The level of HbA1c is lower in physically active participants than non-active participants this study showed that there was no correlation between daily caloric intake and the level of HbA1c. There was no correlation between HbA1c and carbohydrate (p = 0.18), Protein (p = 0.16) and Fat (p = 0.12). In conclusion HbA1c level is decreased by physical activity and not affected by dietary intake. Health education and increase the awareness of the beneficial effects of practicing physical activity, sport and encouraged smoking cessations is very important to control glycemic index, especially in diabetic patients and obese subjects.
How to cite this article:
Ibrahim A. Ali. Association of Glycosylated Hemoglobin with Physical Activity and Diet in Sudanese Non-
Diabetics Population.
DOI: https://doi.org/10.36478/jdme.2020.14.18
URL: https://www.makhillpublications.co/view-article/2708-2709/jdme.2020.14.18