Research Journal of Pharmacology
ISSN: Online 1993-6019ISSN: Print 1815-9362
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Abstract
The purpose of this prospective study is to evaluate the efficacy of dexmedetomidine in a loading dose of 1 mcg kg–1 as an adjuvant to general anaesthesia. This study was carried out in Department of Anaesthesiology, Krishna Institute of Medical Sciences, Karad during a period of 2014-2016. Patients were randomly allocated into two groups of 30 patients each by coded slips for drug combinations. Later at the time of analysis, decoding of slips were done. All patients received Inj. fentanyl 0.001 mg kg–1 and Inj. Midazolam 0.05 mg kg–1 intravenously. They were induced with Inj. thiopentone sodium 5 mg kg–1. Inj. vecuronium 0.12 mg kg–1 was used for neuromuscular blockade. After intubation anaesthesia was maintained with sevoflurane. Extubation was done in routine manner. Patients in Group D took more time compared to Group N to respond to suction catheter, to obey verbal commands and for complete extubation. Though clinically there was not much difference but statistically it was significant, (p<0.05).
How to cite this article:
Avinash G. Bhosale, Mrs. ShraddhaNaik, Mrs. ArchanaGautam, S.A. Pingale and P.B. Patil. The Efficacy of Dexmedetomidine 1 MCG/KG Single Infusion as an Adjuvant for General
Anaesthesia.
DOI: https://doi.org/10.36478/rjpharm.2016.57.61
URL: https://www.makhillpublications.co/view-article/1815-9362/rjpharm.2016.57.61