Research Journal of Medical Sciences
ISSN: Online 1993-6095ISSN: Print 1815-9346
Abstract
To assess the role of hormonal status in the management of breast carcinoma patients. Sixty-eight breast cancer females were selected. The confirmed cases of breast carcinoma patients were proceeded with surgical management followed by adjuvant/neoadjuvant therapy/palliative therapy according to their ER/PR/HER/2 NEU status. After surgery biopsy sent for HPE and IHC for their ER/PR/HER2/neu status chemotherapy/radiotherapy was given. The most common molecular subtype of breast cancer found in our study was Luminal A accounting for 48.53% of the cases. This was followed by Basal type (26.47%) and Luminal B type (20.59%). The most common histology found on final HPE analysis was invasive carcinoma breast no specific type accounting for 72.06% of the patients. This was followed by infiltrating ductal carcinoma accounting for 23.53% of the patients. Majority of ER positive cases 22 out of 48 were in the age group of 50-59 years. Majority of PR positive cases 14 out of 34 were in the age group of 50-59 years. 50% of the patients belonged to luminal A category, 26.47% of the patients belonged to triple negative category, 20.58% of the patients belonged to luminal B category and 2.94% of the patients belonged to Her2neu rich category. Patients with elderly age group are more likely to have hormone receptor status positivity. Hormone receptor-positive tumors are more likely to be larger than those with hormone receptor-negative tumors. Hormone receptor-positive tumors are also more likely to have more lymph node metastasis clinically as well as histologically, whereas according to the literature states the reverse is true.
How to cite this article:
Vinu Gopinath and J.B. Sreelakshmi. Study of Role of Hormonal Status in the Management of Breast Carcinoma in a Hospital Based Study.
DOI: https://doi.org/10.36478/10.59218\makrjms.2023.981.985
URL: https://www.makhillpublications.co/view-article/1815-9346/10.59218\makrjms.2023.981.985