A series of 4-methylphenylsemicarbazone was synthesized and investigated for their antipyretic activity using boiled cow milk induced pyrexia in rabbits. It was observed that the compound 4MS-8 exhibited maximum protection against pyrexia. Hydroxy substitution in aldehydic and acetophenic moiety of 4-methylphenylsemicarbazone derivatives significantly increased antipyretic activity.
Manmohan Singhal and Arindam Paul. 4-Methylphenylsemicarbazone Derivatives Inhibits Cow Milk Induced Pyrexia in Rabbits.
DOI: https://doi.org/10.36478/ijmmas.2011.16.18
URL: https://www.makhillpublications.co/view-article/1813-176x/ijmmas.2011.16.18