Manmohan  Singhal, Arindam  Paul, 
    4-Methylphenylsemicarbazone Derivatives Inhibits Cow Milk Induced Pyrexia in Rabbits,
    International Journal of Molecular Medicine and Advance Sciences,
    Volume 7,Issue 3,
    2011,
    Pages 16-18,
    ISSN 1813-176x,
    ijmmas.2011.16.18,
    (https://makhillpublications.co/view-article.php?doi=ijmmas.2011.16.18)
    Abstract: A series of 4-methylphenylsemicarbazone was synthesized and investigated for their antipyretic activity using boiled cow milk induced pyrexia in rabbits. It was observed that the compound 4MS-8 exhibited maximum protection against pyrexia. Hydroxy substitution in aldehydic and acetophenic moiety of 4-methylphenylsemicarbazone derivatives significantly increased antipyretic activity.
    Keywords: Pyrexia;cow milk;antipyretic;4-methylphenylsemicarbazone;derivatives