International Journal of Molecular Medicine and Advance Sciences
ISSN: Online 1994-4624ISSN: Print 1813-176x
Abstract
Multiple exogenously derived systems of promotion and of induced progression would perhaps actually participate within contextual frameworks of self-promotion as age-related dementia. Indeed, impaired synaptic connectivity and impaired synaptic integrity might assume pathogenic roles leading to aspects of both induced and self-promotion towards pathways of evolving brain atrophy. Even beyond simple schemes of induced effect or of self-progression, however, synaptic transmission or non-transmission might help characterize the Alzheimer process as systems of disturbance arising from micro-circulatory ischemia to lack of neurotrophic effect to systems of nonviability of neurons and of neuronal non-responsiveness. In simple terms, the specific associations of the Alzheimer process with aging would appear a specific characterization of synaptic pathobiology central to basic dynamics of dementia both as an organic atrophic state and also as persistently active pathways of progression once initiated.
How to cite this article:
M. Lawrence. Agius . Loss of Synaptically Determined Viability of Neurons in Alzheimer Brain Atrophy.
DOI: https://doi.org/10.36478/ijmmas.2005.143.148
URL: https://www.makhillpublications.co/view-article/1813-176x/ijmmas.2005.143.148