Journal of Animal and Veterinary Advances
ISSN: Online 1993-601XISSN: Print 1680-5593
Abstract
Calpastatin (CAST) is a specific inhibitor of the ubiquitous calcium-dependent proteases-μ-calpain and m-calpain, found in mammalian tissues. In the coding region of the bovine CAST gene (CAST) the new nucleotide sequence polymorphism was found being a substitution G→C at position 962 nt (consensus sequence-GenBank AF281256). Consensus of bovine CAST sequence with that of human revealed that G→C substitution was located at position 1460 nt of exon 12. Computer analysis of the mutation showed the Ser→Thr substitution for CAST protein. The frequency of alleles C and G was 0.41 and 0.59, respectively. The message from these results is that CAST gene may probably be considered as a candidate marker for beef quality.
How to cite this article:
Dongying Yang. A Novel PCR-RFLP (Xba I) Polymorphism Analysis of the Bovine Calpastatin (CAST) Gene in Chinese Luxi Cattle.
DOI: https://doi.org/10.36478/javaa.2013.788.790
URL: https://www.makhillpublications.co/view-article/1680-5593/javaa.2013.788.790