Journal of Animal and Veterinary Advances
ISSN: Online 1993-601XISSN: Print 1680-5593
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Abstract
Although, the antimicrobial effects of β-Glucan (BG) have been described previously, the use of β-glucan in food animal production has been unrealistic due to high production costs. Recently, pure β-glucan could be efficiently produced by cultivating mutant Aureobasidium pullans which contains a disrupted pul gene and the new method can simplify purification process and reduce mass production costs. Thus, the effect of the β-glucan purified from mutant A. pullans on salmonella infection in weaned pigs was evaluated in the study. Twenty, 4 weeks old pigs were randomly assigned to the following 4 groups: BG or BG-X group was provided with commercial feeds containing β-glucan (10 mg kg-1) or containing both β-glucan (10 mg kg-1) and Genkwadaphnin (10 mg kg-1), respectively; Normal Feed (NF) and Negative control (Neg.) groups were only provided with commercial feeds only. All the groups were provided with their specific diets for 2 weeks, challenged with Salmonella Typhimurium at 108 Colony Forming Units (CFU)/mL except for the Neg. group and sacrificed for pathological evaluation at 4 weeks after the challenge. As compared with the NF group, BG and BG-X groups showed significantly lower diarrhea incidence and salmonella shedding in feces and gained more weight after salmonella infection. Gross lesions were less severe in BG and BG-X groups but the differences reached no statistical significance. In conclusion this study demonstrated that the overall performance of weaned pigs fed β-glucan derived from A. pullan was enhanced upon challenge with salmonella by increasing weight gains and reducing both the incidence of diarrhea and fecal shedding of salmonella.
How to cite this article:
Nadeem Shabir, Byung-Dae Yoon, Amina Khatun, Bum-Seok Kim, Ji-Hoon Shin, Keug-Hyun Ahn and Won-Il Kim. Effects of Dietary Addition of β-Glucan on Pigs Infected with Salmonella Typhimuriu.
DOI: https://doi.org/10.36478/javaa.2013.1657.1664
URL: https://www.makhillpublications.co/view-article/1680-5593/javaa.2013.1657.1664