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Journal of Animal and Veterinary Advances

ISSN: Online 1993-601X
ISSN: Print 1680-5593
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A Novel Method Based on Ligase Detection Reaction for PGC-1α G646A Gene Polymorphism and its Genetic Effect on Meat Quality in Chicken

Chen Kuan-Wei, Zang Ying, Shan Yan-Ju, Xu Wen-Juan, Li Hui-Fang and Shu Jing-Ting
Page: 2921-2925 | Received 21 Sep 2022, Published online: 21 Sep 2022

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Abstract

The Peroxisome Proliferators-activated receptor-γ Coactivator-1α (PGC-1α) was investigated as a candidate gene for meat quality and fatness traits in chicken because of its prominent role in muscle fiber specialization and adipogenesis. Variations of PGC-1α+646G/A may associate with chicken meat quality traits. The objective of the current research was to investigate the association of this single nucleotide polymorphisms in PGC-1α gene with meat quality traits in Recessive White chickens and Qingyuan Partridge chickens. Genotyping was performed by Polymerase Chain Reaction-Ligation Detection Reaction (PCR-LDR) Method. Marker-trait association analysis indicated that there were significant associations between G646A genotypes and the trait of water loss rate. Researchers putatively drew the conclusion that this SNP in PGC-1α gene could be used as the potential molecular marker for meat quality trait in chicken.


How to cite this article:

Chen Kuan-Wei, Zang Ying, Shan Yan-Ju, Xu Wen-Juan, Li Hui-Fang and Shu Jing-Ting. A Novel Method Based on Ligase Detection Reaction for PGC-1α G646A Gene Polymorphism and its Genetic Effect on Meat Quality in Chicken.
DOI: https://doi.org/10.36478/javaa.2011.2921.2925
URL: https://www.makhillpublications.co/view-article/1680-5593/javaa.2011.2921.2925