Li  Hui-Fang, Chen  Kuan-Wei, Zang  Ying, Shan  Yan-Ju, Xu  Wen-Juan, Shu  Jing-Ting, 
    A Novel Method Based on Ligase Detection Reaction for <I>PGC-1&#945; G646A</I> Gene Polymorphism and its Genetic Effect on Meat Quality in Chicken,
    Journal of Animal and Veterinary Advances,
    Volume 10,Issue 22,
    2011,
    Pages 2921-2925,
    ISSN 1680-5593,
    javaa.2011.2921.2925,
    (https://makhillpublications.co/view-article.php?doi=javaa.2011.2921.2925)
    Abstract: The Peroxisome Proliferators-activated receptor-&#947; Coactivator-1&#945; (PGC-1&#945;) was investigated as a candidate gene for meat quality and fatness traits in chicken because of its prominent role in muscle fiber specialization and adipogenesis. Variations of PGC-1&#945;+646G/A may associate with chicken meat quality traits. The objective of the current research was to investigate the association of this single nucleotide polymorphisms in <I>PGC-1&#945;</I> gene with meat quality traits in Recessive White chickens and Qingyuan Partridge chickens. Genotyping was performed by Polymerase Chain Reaction-Ligation Detection Reaction (PCR-LDR) Method. Marker-trait association analysis indicated that there were significant associations between G646A genotypes and the trait of water loss rate. Researchers putatively drew the conclusion that this SNP in <I>PGC-1&#945; </I>gene could be used as the potential molecular marker for meat quality trait in chicken.
    Keywords: China;PGC-1a gene;ligase detection reaction;chicken;polymorphism;meat quality