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Journal of Animal and Veterinary Advances

ISSN: Online 1993-601X
ISSN: Print 1680-5593
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Intracerebroventricular Injection of Glutathione Suppresses Food Intake of Neonatal Chicks

H. Yamane , S. Tomonaga , R. Suenaga , D.M. Denbow and M. Furuse
Page: 1247-1249 | Received 21 Sep 2022, Published online: 21 Sep 2022

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Abstract

It is well known that a single deficiency or excess of a Sulfur-containing Amino Acid (SAA), a major determinant of the glutathione concentration in some tissues, decreased food intake of chicks. To clarify the central function of glutathione on food intake, the effect of intracerebroventricular (i.c.v.) injection of reduced Glutathione (GSH) (0.5, 1.0, 2.0 µmol) was investigated in fasting neonatal chicks. Food intake was suppressed by GSH in a dose-dependent manner over 120 min. It was suggested that the reduction in food intake induced by SAA excess, but not SAA deficiency, may be associated with GSH in the brain.


How to cite this article:

H. Yamane , S. Tomonaga , R. Suenaga , D.M. Denbow and M. Furuse . Intracerebroventricular Injection of Glutathione Suppresses Food Intake of Neonatal Chicks.
DOI: https://doi.org/10.36478/javaa.2007.1247.1249
URL: https://www.makhillpublications.co/view-article/1680-5593/javaa.2007.1247.1249