TY - JOUR T1 - Intracerebroventricular Injection of Glutathione Suppresses Food Intake of Neonatal Chicks AU - , H. Yamane AU - , S. Tomonaga AU - , R. Suenaga AU - , D.M. Denbow AU - , M. Furuse JO - Journal of Animal and Veterinary Advances VL - 6 IS - 11 SP - 1247 EP - 1249 PY - 2007 DA - 2001/08/19 SN - 1680-5593 DO - javaa.2007.1247.1249 UR - https://makhillpublications.co/view-article.php?doi=javaa.2007.1247.1249 KW - Reduced glutathione KW -food intake KW -intracerebroventricular injection KW -neonatal chick AB - It is well known that a single deficiency or excess of a Sulfur-containing Amino Acid (SAA), a major determinant of the glutathione concentration in some tissues, decreased food intake of chicks. To clarify the central function of glutathione on food intake, the effect of intracerebroventricular (i.c.v.) injection of reduced Glutathione (GSH) (0.5, 1.0, 2.0 µmol) was investigated in fasting neonatal chicks. Food intake was suppressed by GSH in a dose-dependent manner over 120 min. It was suggested that the reduction in food intake induced by SAA excess, but not SAA deficiency, may be associated with GSH in the brain. ER -