International Journal of Tropical Medicine
ISSN: Online 1818-779XISSN: Print 1816-3319
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A Study of the Clinical, Haematological and Biochemical Profiles of Individuals in North India with Dengue Virus Infections Implications for Patient Management
Sujata , Gurmeet Kaur, Ankita and Manish Kumar
Page: 43-47 | Received 25 Oct 2023, Published online: 01 Nov 2023
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Abstract
Dengue fever is a mosquito borne arboviral disease that is a serious global public health. Problem, mostly in tropical and subtropical regions of the world. Dengue fever is present mainly in Africa, South‐East Asia, Western Pacific and Caribbean. Infection with a specific dengue serotype results in lasting homotypic immunity against that particular serotype. Multiple serotypes may circulate simultaneously during an epidemic, potentially leading to an individual multiple infections, each corresponding to a distinct serotype. Dengue infection can be identified using clinical signs and laboratory investigations. Both non‐specific and specific diagnostic measures are use in the evaluation of dengue. To underscore the most common clinical parameters, along with the haematological and biochemical investigations, among cases of dengue. A cross‐sectional prospective study was conducted at Dengue ward in Atal Bihari Vajpayee institute of medical sciences and Dr. Ram Manohar Lohia Hospital, New Delhi from October 2021 December 2021. A physician performed clinical examinations on each research participant. Demographic characteristics and clinical profiles of research participants were obtained by nurses using a structured questionnaire, as previously published. A total of 450 febrile patients, who were suspected of having dengue virus infection according to the WHO criteria from 2009, underwent testing for dengue‐specific IgM antibodies. Among these, 120 patients were confirmed to be positive for dengue. In 99 patients the most prevalent haematological finding was thrombocytopenia (platelet count 150,000/cumm) (96/99‐96.9) then anaemia (haemoglobin level) in 37 (37/99‐37.3%) and leukopenia (total) in 31 (31/99‐31.1%). The commonest clinical feature was fever, 96 (96.9%) followed by headache in 92 (92/99‐92.9%) myalgia 82 (82/99‐82.8%) nausea/vomiting 46 (46/99‐46.4%) abdominal pain 49(49/99‐49.4%) eye pain and mucosal bleeding 25 (25/99‐25.2%) in each of the cases. This study highlights that the most frequently reported symptoms among dengue patients were fever, headache and myalgia. Similarly, the prevalent observations included thrombocytopenia, anaemia, leukopenia and elevated AST levels. These findings serve as awarning to healthcare professionals, signalling the potential occurrence of dengue infection within the study region. Dengue, Fever, Haemorrhage, Thrombocytopenia, Anaemia.
How to cite this article:
Sujata , Gurmeet Kaur, Ankita and Manish Kumar. A Study of the Clinical, Haematological and Biochemical Profiles of Individuals in North India with Dengue Virus Infections Implications for Patient Management.
DOI: https://doi.org/10.36478/10.59218/makrjms.2023.3.43.47
URL: https://www.makhillpublications.co/view-article/1816-3319/10.59218/makrjms.2023.3.43.47