Diagnosis of malaria has always been a diagnostic challenge in endemic areas. More than 90% of malaria cases and the most severe and possibly fatal diseases are caused by Plasmodium falciparum. For many centuries microscopy‐based diagnosis has been a gold standard method. Despite the presence of expert microscopists, laboratory misdiagnosis of malaria is still a problem. The HORIBA Medical Haematology Analyzer, Yumizen H550, provides flags for Plasmodium falciparum Malaria developed through machine learning methods. It can be used as a screening tool for Plasmodium falciparum Malaria in endemic areas. This study aimed to evaluate the sensitivity and specificity of these flags. The study done in Western India from July‐2022 to April‐2023. Total 200 patients were included. 100 febrile patients having Plasmodium falciparum malaria diagnosis and 100 healthy nonfebrile patients with normal lab investigations were included in study. Microscopic examination was considered as the confirmatory method for Malaria. Rapid malarial antigen tests were used for additional confirmation. In our study, at cut off point of 0.50, Sensitivity and specificity for Plasmodium falciparum was 13‐100%, respectively. Horiba Yumizen H 550 cell counter gives low sensitivity (13%) at cut off 0.5 for plasmodium falciparum malaria flag.
Dinesh A. Rathod, Nita D. Rathod, Viral J. Patel, Amit Maniyar and Mahima J. Patel. Utility and Reliability of Plasmodium falciparum Malaria Flag on Horiba Yumizen H 550 Cell Counter.
DOI: https://doi.org/10.36478/10.59218/makrjms.2023.2.87.90
URL: https://www.makhillpublications.co/view-article/1816-3319/10.59218/makrjms.2023.2.87.90