International Journal of Tropical Medicine
ISSN: Online 1818-779XISSN: Print 1816-3319
Abstract
Acute pancreatitis (AP) presents a spectrum of severity, necessitating early and accurate severity assessment for optimal management. This study evaluates the utility of the Neutrophil‐Lymphocyte Ratio (NLR), serum bilirubin levels and the Bedside Index of Severity in Acute Pancreatitis (BISAP) score as prognostic markers in AP. This retrospective cohort study included 75 consecutive AP patients admitted to the Department of General Surgery at Mamata Medical College. Data on demographic, clinical presentation, laboratory parameters, scoring systems and clinical outcomes were collected. The NLR was calculated using absolute neutrophil and lymphocyte counts. Serum bilirubin levels were measured with standard laboratory techniques and the BISAP score was calculated for each patient. Descriptive statistics and analysis focused on the association between these markers and AP severity.The mean age was 52.4 years, with a 60% male predominance. Gallstones (50%) and alcohol (30%) were the primary etiologies. The mean neutrophil count was 8500 cells/mm³, lymphocyte count 2200 cells/mm³, serum bilirubin 1.5 mg/dL, BUN 18 mg/dL and serum albumin 3.6 g/dL. The mean BISAP score was 3.2, with distribution across the severity spectrum of AP. Mild, moderate and severe AP were observed in 40%, 33.3% and 26.7% of patients, respectively. The mean hospital stay was 7.5 days, 20% required ICU admission and the mortality rate was 6.7%. The study confirms the predictive value of NLR, serum bilirubin levels and the BISAP score in assessing AP severity. Elevated NLR and bilirubin levels, along with higher BISAP scores, correlate with increased AP severity, underscoring their utility in early risk stratification and management decisions.
How to cite this article:
K. Anand Goud. Assessment of Neutrophil‐Lymphocyte Ratio, Serum Bilirubin Levels and Bedside Index of Severity in Predicting Acute Pancreatitis Severity.
DOI: https://doi.org/10.36478/10.59218/makijtm.2024.2.7.11
URL: https://www.makhillpublications.co/view-article/1816-3319/10.59218/makijtm.2024.2.7.11