International Journal of Tropical Medicine
ISSN: Online 1818-779XISSN: Print 1816-3319
Abstract
Pheochromocytoma remains an endocrine enigma to diagnose and treat in spite of striking advances in chemical assaying, radio‐imaging and simultaneous better understanding of the pathophysiology and its varied clinical presentations, advances in antihypertensive drug therapy and anesthetic and surgical techniques. To study clinical presentation, methods of diagnosis and management of pheochromocytoma, with aim to determine whether; Clinical diagnosis was established prior to surgery. This observational study was conducted in the Department of Endocrinology and Oncology, at Tertiary care Hospital, Bangalore, Karnataka. In addition to hypertensive crisis (systolic blood pressure >220 mmHg and/or diastolic blood pressure >120mmHg) and/or hypotension (systolic blood pressure <90 mmHg and/or diastolic blood pressure <60 mmHg), PPGL crisis was defined as the acute and severe presentation of catecholamine‐induced hemodynamic instability causing end‐organ damage or dysfunction. Some patients (25%) had extra adrenal Pheochromocytoma (paragangliomas), rest all (75%) had adrenal with one bilateral. All four had histology consistent with pheochromocytoma. Along with that 25% patients having all clinical evaluations suggestive of nonfunctioning adrenal tumor had operative complications with histology proving pheochromocytoma. High index of suspicion in patients with clinical features suggestive is required for early diagnosis of this medically challenging problem. In spite of striking advances in diagnostic methods there still remains considerable difficulty and delay in establishing diagnosis, thus leading to adverse clinical implications. Nuclear Imaging with newer tracer materials are promising, although sensitivity and specificity has to be established with larger series.
How to cite this article:
K.N. Satish Babu and Jagannath Dixit. Composite Pheochromocytoma in Patients with Surgical Removal of Tumours in the Adrenal Region.
DOI: https://doi.org/10.36478/10.59218/makijtm.2024.2.59.62
URL: https://www.makhillpublications.co/view-article/1816-3319/10.59218/makijtm.2024.2.59.62