International Journal of Tropical Medicine
ISSN: Online 1818-779XISSN: Print 1816-3319
Abstract
During pregnancy, a woman's nutritional requirements significantly differ from those in non‐pregnant states. The nutrients necessary for fetal growth and development throughout the nine months of pregnancy are primarily derived from the mother's body and its reservoirs of vitamins and minerals. The objective of this study was to assess calcium deficiency and its correlation with various biochemical parameters throughout the three stages of pregnancy in Indian women. Blood samples were collected from 78 pregnant women diagnosed by specialists, aged between 17 to 50 years, from an Indian General Hospital. Additionally, 45 healthy women of similar ages were included as a control group. The study measured levels of calcium, vitamin D, parathyroid hormone (PTH), alkaline phosphates (ALP), phosphorous and albumin. The findings revealed elevated levels of vitamin D, PTH, ALP and albumin in pregnant women compared to the control group, while calcium levels were lower in pregnant women. Specifically, PTH and albumin were lower during the first trimester, whereas calcium and phosphorus were lower during the third trimester. ALP levels were lower in the second trimester and vitamin D significantly decreased in the third trimester. The study also observed a negative correlation between calcium and PTH levels, while calcium exhibited a weak positive correlation with vitamin D, albumin and phosphorus. The relationship between calcium and ALP was also weakly positive. Based on these results, it can be concluded that low calcium levels are associated with pregnancy and may indicate an increased risk of osteoporosis in women.
How to cite this article:
Shashank Tyagi, Gaurav Akhand, Deepika Anuragi and Sonendra Kumar Sharma. A Study of Correlation between Calcium Deficiency and Risk of Osteoporosis in Pregnant Women.
DOI: https://doi.org/10.36478/10.59218/makijtm.2024.2.30.33
URL: https://www.makhillpublications.co/view-article/1816-3319/10.59218/makijtm.2024.2.30.33