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International Journal of Tropical Medicine

ISSN: Online 1818-779X
ISSN: Print 1816-3319
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Lipid Profile Variations and Liver Function in Alcoholic Fatty Liver Disease vs. Non‐Alcoholic Fatty Liver Disease: A Comparative Study

Dipti Ranjan Darjee, Sanjay Kumar Behera, Sudipti Sahu and Aditya Narayan Sahu
Page: 25-29 | Received 12 Oct 2023, Published online: 30 Oct 2023

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https://doi.org/10.36478/10.59218/makijtm.2023.3.25.29

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Abstract

Individuals with both NAFLD and AFLD exhibit abnormalities in lipid parameters and liver enzymes. This study was conducted with the aim of conducting a comparative analysis of the lipid profile and liver function tests in persons diagnosed with Alcoholic Fatty Liver Disease (AFLD) and Non‐Alcoholic Fatty Liver Disease (NAFLD). This cross‐sectional study was conducted on 50 AFLD and 50 NAFLD patients. The lipid parameters and liver function tests were analyzed using established methodologies on a Biosystem BA‐400 chemistry analyzer. The statistical analysis was conducted with IBM SPSS Statistics 20. Patients with AFLD displayed markedly elevated levels of total cholesterol (TC), triglycerides (TG), low‐density lipoprotein (LDL), and very low‐density lipoprotein (VLDL) in contrast to NAFLD patients. Conversely, AFLD patients exhibited a significant reduction in high‐density lipoprotein (HDL) levels when compared to those with NAFLD. Patients with AFLD demonstrated higher serum levels of aspartate aminotransferase (AST), total bilirubin, and the AST/ALT ratio when compared to individuals with NAFLD. To sum up, individuals diagnosed with alcoholic fatty liver disease as well as those with non‐alcoholic fatty liver disease displayed dyslipidemic lipid marker patterns and abnormal liver function test results.

How to cite this article:

Dipti Ranjan Darjee, Sanjay Kumar Behera, Sudipti Sahu and Aditya Narayan Sahu. Lipid Profile Variations and Liver Function in Alcoholic Fatty Liver Disease vs. Non‐Alcoholic Fatty Liver Disease: A Comparative Study.
DOI: https://doi.org/10.36478/10.59218/makijtm.2023.3.25.29
URL: https://www.makhillpublications.co/view-article/1816-3319/10.59218/makijtm.2023.3.25.29