Chronic kidney disease (CKD) is a progressive condition characterized by a gradual loss of kidney function over time. This study aimed to evaluate the extent of kidney damage and dysfunction in patients with CKD through detailed radiological imaging and biochemical markers. This cross-sectional study included 35 patients diagnosed with CKD. Radiological imaging involving abdominal ultrasound, CT scans, MRI and renal scintigraphy were used to assess kidney structure and function. Biochemical parameters including serum creatinine, blood urea nitrogen (BUN), estimated glomerular filtration rate (eGFR) and additional metabolic markers were measured to evaluate renal function. Radiological imaging showed normal kidney dimensions with small renal masses and benign cysts. Mild renal artery stenosis was noted via MRI and renal scintigraphy reflected normal perfusion and GFR. Biochemical analysis indicated renal impairment with elevated serum creatinine, increased BUN and reduced eGFR. Patients also presented with anemia, mineral metabolism abnormalities, hypoalbuminemia, hyperkalemia, dyslipidemia and significant proteinuria. The integration of radiological imaging with biochemical markers provides a robust framework for assessing the extent and impact of CKD. The findings align with the structural and functional changes observed in CKD, necessitating an interdisciplinary approach to management and intervention.
Krishna Sumanth, E. Praveen, P. Hanumantha Rao and M. Soundara Pandian. Radiological and Biochemical Evidence in Patients with Chronic Renal Failure: An Institutional Study.
DOI: https://doi.org/10.36478/10.59218/makijtm.2023.3.10.14
URL: https://www.makhillpublications.co/view-article/1816-3319/10.59218/makijtm.2023.3.10.14