International Journal of Tropical Medicine
ISSN: Online 1818-779XISSN: Print 1816-3319
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Abstract
Polycystic ovary syndrome (PCOS) is a heterogeneous metabolic disorder. It is one of the important reasons for infertility. PCOS is the most common cause of irregular menstruation with diverse clinical manifestations affecting women of reproductive age. The present study aimed to examine systemic inflammatory markers such as neutrophil–lymphocyte ratio (NLR), C-reactive protein (CRP) and mean platelet volume (MPV), in patients with PCOS and to compare them with healthy women. This was a cross sectional study, enrolled PCOS patients and same number of age matched healthy women as a control. We have compared both the groups (PCOS and control) in respect to biochemical and hematological markers. Laboratory investigation of TLC, neutrophils count, lymphocytes count, platelets counts, NLR, MPV, PLR, serum glucose, CRP, lipid profile, LH, FSH, TSH and other markers was done. A total of 230 participants (115 were PCOS cases and 115 healthy Control) were analysed. The age distribution, waist circumference and BMI were statistically significantly higher in the PCOS group compared to the control group (p<0.05). All inflammatory markers like: TLC, neutrophils count, CRP, NLR and lipid profile were significantly higher in PCOS group (p<0.05) PCOS women typically present with an increased NLR and CRP, Such an increase is independent of obesity and may be associated with glycolipid metabolic disorders
How to cite this article:
Soobia Karim Ansari, Dharmveer Sharma and Vidyanand Pandit. Assessment of Neutrophil to Lymphocyte Ratio, C-reactive Protein and Mean Platelet Volume in Polycystic Ovary Syndrome.
DOI: https://doi.org/10.36478/10.59218/makijtm.2023.2.46.49
URL: https://www.makhillpublications.co/view-article/1816-3319/10.59218/makijtm.2023.2.46.49