International Journal of Tropical Medicine
ISSN: Online 1818-779XISSN: Print 1816-3319
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Abstract
Ventilator-associated pneumonia (VAP) is a common complication of ventilatory support for patients with acute respiratory failure. It is a leading cause of increased morbidity and mortality in critically ill patients. The present study was undertaken to isolate aerobic bacteria, their antibiotic susceptibility from the endotracheal aspirates and clinical outcome in patients of VAP. This cross sectional study was performed over a period of one year in a tertiary care hospital, enrolling ICU patients on mechanical ventilation (MV) for >48 hrs. Endotracheal aspirates (ETA) were collected from patients with suspected VAP, direct gram’s staining and cultures of ETA were performed. Identification of isolates were done by standard methods, AST was done by Kirby bear disk diffusion test. Microbiological diagnosis of VAP was taken as >105 colony forming units CFU mL‾1. Out of 110 cases, half of them were 30-45 years age group, predominantly male (59.1%). Late onset VAP was more common (60.38%) than early onset VAP. Acinetobacter baumannii and Pseudomonas aeruginosa were the most common bacterial isolates. On x-ray finding Acinetobacter baumannii mainly found bilateral (40.1%). Most of the isolates were Multi drug resistant. The early identification of bacterial isolates and their sensitivity pattern helps the clinicians in choosing the appropriate antibiotics and prompt management of VAP.
How to cite this article:
Manish Kumar, Nandini Shukla, Brajesh Sharma and Shashank Tyagi. Microbial Profile, Susceptibility Patterns and Clinical Outcome of Ventilator-Associated Pneumonia in an Intensive Care Unit.
DOI: https://doi.org/10.36478/10.59218/makijtm.2023.2.35.39
URL: https://www.makhillpublications.co/view-article/1816-3319/10.59218/makijtm.2023.2.35.39