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International Journal of Tropical Medicine

ISSN: Online 1818-779X
ISSN: Print 1816-3319
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Correlation of Optical Coherence Tomography (OCT) Guided Macular Thickness Changes with Lipid Profile Values and Estimated Glomerular Filtration Rate in Type 2 Diabetes Mellitus Patients

Anirudh Sharma , Sardar Mohd. Akram, Khalida Sayeed , Rubie Malhotra , Pooja Kanodia and Akansha Srivastava
Page: 34-38 | Received 30 Dec 2022, Published online: 01 Apr 2023

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https://doi.org/10.36478/10.59218/makijtm.2022.34.38

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Abstract

The aim of this present study was to correlate the optical coherence tomography (OCT) guided macular thickness changes with lipid profile values and estimated glomerular filtration rate in type 2 diabetes mellitus patients. OCT macular scanning (both eyes) was done, with the help of Zeiss Primus 200 (SD-OCT) and the OCT parameters used were Central Subfoveal Thickness (CST), Cube Volume (CV) and Cube Average Thickness (CAT). All patients underwent specific blood investigations which included lipid profile and serum creatinine. The GFR was calculated by Cockcroft-gault formula. The result was analyzed using descriptive statistics and making comparisons among various groups. Categorical data were summarized as in proportions and percentage while discrete as Mean±SD. Group of 51-60 years, 122 (51.7%) were female and 114(48.3%) were males. Of the 236 study participants total cholesterol levels were normal (<200 mg dL‾1) in 178 had and raised (>200 mg dL‾1) in 58 cases; low density lipoprotein (LDL) levels were normal (<100 mg dL‾1) in 178 and raised (>100 mg dL‾1) in 58 cases and serum triglyceride levels were normal (<150 mg dL‾1) in 182 and raised (>150 mg dL‾1) in 54 cases. The estimated Glomerular Filtration Rate (eGFR) was below normal (<60 mL min‾1 1.73 mm‾2) in 29 cases and normal in the remaining 207 cases. Our study concluded that optimal control of various systemic parameters that affect the onset and progression of DR and DME through a multidisciplinary healthcare team approach involving the physician, the ophthalmologist and the dietician/counselor for early detection and timely treatment could help in reducing the visual morbidity due to Diabetic Retinopathy.

How to cite this article:

Anirudh Sharma , Sardar Mohd. Akram, Khalida Sayeed , Rubie Malhotra , Pooja Kanodia and Akansha Srivastava . Correlation of Optical Coherence Tomography (OCT) Guided Macular Thickness Changes with Lipid Profile Values and Estimated Glomerular Filtration Rate in Type 2 Diabetes Mellitus Patients.
DOI: https://doi.org/10.36478/10.59218/makijtm.2022.34.38
URL: https://www.makhillpublications.co/view-article/1816-3319/10.59218/makijtm.2022.34.38