International Journal of Tropical Medicine
ISSN: Online 1818-779XISSN: Print 1816-3319
Abstract
Recent research indicates that men with impaired glucose regulation (pre‐diabetes) or diabetes exhibit lower serum total testosterone (TT) levels compared to normoglycemic men. In India, there is a high incidence and prevalence of diabetes mellitus (DM) and pre‐diabetes among the middle‐aged population. While most studies have focused on serum TT levels in elderly men with pre‐diabetes or diabetes, there is a notable lack of data concerning this association in middle‐aged men. The objectives of this study were to investigate the serum TT levels in middle‐aged men with DM or pre‐diabetes and compare them with normoglycemic men. This cross‐sectional, observational study included 178 nonsmoking, non‐tobacco using and non‐alcoholic men aged between 31 and 60 years. Anthropometric measurements, serum FBG levels and serum TT levels were assessed. Men with pre‐diabetes and diabetes demonstrated significantly lower serum TT levels compared to non‐diabetic men. Additionally, serum TT levels were found to negatively correlate with WC, BMI and blood glucose levels, with a significant correlation observed specifically with WC. Low serum TT levels are associated with both pre‐diabetes and diabetes. Further prospective studies are needed to determine whether this association is causal.
How to cite this article:
Varsha Patel, Jyoti Shukla, Arunendra Deepankar Nirat and Shashank Tyagi. Testosterone Deficiency and Its Association with Impaired Blood Glucose: A Cross Sectional Study.
DOI: https://doi.org/10.36478/10.36478/makijtm.2024.3.75.78
URL: https://www.makhillpublications.co/view-article/1816-3319/10.36478/makijtm.2024.3.75.78