International Journal of Tropical Medicine
ISSN: Online 1818-779XISSN: Print 1816-3319
Abstract
To study the histological changes in the gallbladder for which cholecystectomy was required. Permission to conduct research using human subjects was obtained from the Research and Ethical Committee of the Index Medical College, Hospital and Research Centre, Malwanchal University. Histological assessment was performed on all 60 cases, resulting in the categorization of tissue samples based on their mucosal response patterns. Cases with multiple mucosal responses per specimen were assigned a predominant pattern. The majority of these cases displayed chronic inflammation, with chronic cholecystitis being the most prevalent, affecting 47 patients. Five cases showed chronic cholecystitis with metaplasia, while two cases were diagnosed with carcinoma. Interestingly, all patients with carcinoma were female. After analyzing the relationship between mucosal response and gallstone type, the chi‐square test yielded a value of x2=3.824 and a P‐value of 0.867, indicating no significant association. However, when examining the association between mucosal response and gallstone size, the test statistics revealed a value of 12.923 and a P<0.05, suggesting a significant relationship. Chronic cholecystitis can exhibit various histo‐morphological patterns, such as acute on chronic cholecystitis and xantho‐granulomatous cholecystitis. This condition can occur with cholelithiasis at any age, as observed in this study group, where chronic calculous cholecystitis was the most common finding. Additionally, pigment stones were the most frequently identified type of stone, as opposed to mixed and cholesterol stones.
How to cite this article:
Pawan Kumar Mahato and Rajesh Kumar Jha. Study of Histopathological Examination of Gallbladder After Cholecystectomy.
DOI: https://doi.org/10.36478/10.36478/makijtm.2024.3.116.120
URL: https://www.makhillpublications.co/view-article/1816-3319/10.36478/makijtm.2024.3.116.120