In developing nations such as India, diseases like dengue, malaria typhoid are endemic and often manifest as acute undifferentiated fever. In areas where multiple infectious agents coexist, the incidence of co‐infections is higher. In tropical regions, seasonal variations increase the risk of individuals being co‐infected with dengue and other infectious diseases such as rickettsia, malaria enteric fever. This study aimed to examine the association of co‐infections in children diagnosed with dengue. In this retrospective hospital‐based study, case records of all patients diagnosed with dengue and admitted during this period were reviewed. The study included patients admitted to ward and ICU who tested positive for NS1, IgM, or IgG. Patients with dengue‐like symptoms but serologically negative were excluded. A total of 245 patients were admitted with serologically confirmed dengue during the study period. Of these, 143 (58.37%) were female and 102 (41.63%) were male, 215 (87.76%) were from rural areas 30 (12.24%) were from urban areas. Among the 245 patients, 33 had co‐infections. Of these, 19 (57.58%) had enteric fever, 8 (24.24%) had malarial fever, 3 (9.09%) had rickettsial fever 2 (6.06%) had urinary tract infections (UTIs). Co‐infection was more frequent in patients with dengue with warning signs and severe dengue, which was statistically significant (p<0.05). Children with co‐infections had longer hospital stays mortality was higher among patients with severe dengue and co‐infections. Co‐infections with enteric fever, malaria, rickettsia UTIs are not uncommon in patients with dengue fever. Children with co‐infections present with more severe dengue and have extended hospital stays.
Nazir Ahmad Var, Poonam Sunil Pagare, Priyanka Purushottam Chaubey and Sangeeta Dudve. Assessment of Clinical Profile and Treatment Outcome of Children With Dengue and Co‐Infections.
DOI: https://doi.org/10.36478/10.36478/makijtm.2024.2.125.128
URL: https://www.makhillpublications.co/view-article/1816-3319/10.36478/makijtm.2024.2.125.128