International Journal of Tropical Medicine
ISSN: Online 1818-779XISSN: Print 1816-3319
Abstract
Pancytopenia is a condition where all the three formed cells, i.e RBC, WBC, PLATLETS, are below the normal reference range. various conditions ranging from simple drug induced bone marrow hypoplasia, megaloblastic marrow to fatal bone marrow aplasia and leukemias presents as pancytopenia. Underlining pathology and severity of pancytopenia determines the management and prognosis. Thus, identification of etiology help in implementing appropriate therapy. To study on clinical profile of pancytopenia with special reference to bone marrow picture. Study was conducted at department of medicine, K R hospital, Mysuru from Jan 2019 to June 2020.Total 35 patients of pancytopenia were studied to determine their clinical features, peripheral smear, bone marrow morphology. Patients explained completely regarding the study and taken consent. etiology was assessed by relevant investigations in respective patients. Commonest age group affected is 31‐40 years . Males accounted for 19 cases (54%), females 16 cases (46%). Commonest presenting complaint was easy fatigability followed by bleeding manifestations. Common physical finding was pallor Other signs and symptoms were fever, breath less ness, bone pain, hepatomegaly, splenomegaly, petechial hemorrhages and lymphadenopathy. Megaloblastic anemia is most common cause of pancytopenia followed by hypersplenism, aplastic anemia and malignancies. The physical findings, peripheral blood picture and bone marrow evaluation provides valuable information. From our study it can be proposed that inspite of numerous etiology available for pancytopenia the most common etiology is megaloblastic anemia. and most common reason for megaloblastic anemia is Vit B12 deficiency.
How to cite this article:
L. Vikas, G.S. Pradeep and Riyaz Ahmed. Study on Clinical Profile Of Pancytopenia with Special Reference to Bone Marrow Picture.
DOI: https://doi.org/10.36478/10.36478/makijtm.2024.2.115.118
URL: https://www.makhillpublications.co/view-article/1816-3319/10.36478/makijtm.2024.2.115.118