International Journal of Tropical Medicine
ISSN: Online 1818-779XISSN: Print 1816-3319
Abstract
Chronic hepatitis B (CHB) can lead to liver fibrosis, a major health concern due to its potential to progress to cirrhosis and liver cancer. Recognizing the risk factors for liver fibrosis in CHB patients is pivotal for effective clinical management and intervention. In this cross‐sectional study, 150 CHB patients were enrolled. Comprehensive data collection was done, encompassing demographic information, clinical history, biochemical markers and virological profiles. The assessment of liver fibrosis was done using [specific method, e.g., liver biopsy, elastography]. Both univariate and multivariate logistic regression analyses were employed to discern the risk factors associated with liver fibrosis. Of the 150 participants, 60 (40.0%) exhibited signs of significant liver fibrosis. The analysis indicated a strong association between liver fibrosis and certain factors such as older age (>50 years) (OR = 2.3, 95% CI = 1.5‐3.4), elevated HBV DNA levels (OR = 2.5, 95% CI = 1.6‐3.9) and duration of infection (OR = 2.2, 95% CI = 1.4‐3.5). This study underscores the importance of several risk factors in the development of liver fibrosis among CHB patients. Early detection and proactive management based on these identified risk factors might mitigate the progression to more severe liver complications. Further research, especially longitudinal studies, would be valuable in reaffirming these findings.
How to cite this article:
Sunita Surendra Kadam and Surendra Punjarao Kadam. Risk Factors for Liver Fibrosis in Patients with Chronic Hepatitis B: A Cross‐Sectional Study.
DOI: https://doi.org/10.36478/10.36478/makijtm.2023.4.100.104
URL: https://www.makhillpublications.co/view-article/1816-3319/10.36478/makijtm.2023.4.100.104