Research Journal of Pharmacology
ISSN: Online 1993-6019ISSN: Print 1815-9362
Abstract
Eszopiclone is a type of medicine used in the treatment of insomnia with a hypnotic effect. The aim of this study is to create Eszopiclone 3 mg tablet formulation by providing homogeneous distribution of Eszopiclone raw material which is found in low amount in the drug, into the Excipients. In order to achieve homogeneous blending, 4 trial production and pilot studies were carried out using the geometric blending and elimination method. Trial 4 was optimized and the process validation study was approved. Acceptable content uniformity values of trial 4 and pilot study were calculated as 8.63 and 8.74%, respectively. In this study, the importance of geometric blending and elimination method is shown.
How to cite this article:
Kübra Kol, Cüneyt Toprak and Gökay Gün. Development of Low Dose Eszopiclone Drug Formulation by Using Geometric Blending
Method.
DOI: https://doi.org/10.36478/rjpharm.2020.44.48
URL: https://www.makhillpublications.co/view-article/1815-9362/rjpharm.2020.44.48