Research Journal of Pharmacology
ISSN: Online 1993-6019ISSN: Print 1815-9362
Abstract
Natural products, attendant from plants, microbes and marine living organisms, give the broadest range of chemical diversity of deep‐seated biological significance. Study of the intricate chemistry and diverse biological activity of natural products should therefore be undertaken to underscore their potential as sources of therapeutic agents and pharmaceutical leads. Natural products are then divided into some distinct chemical classes concerning the unique structural features of biosynthetic pathways. Those prominent classes that show a wide range of pharmacological properties include terpenoids, alkaloids, polyphenols, peptides and proteins. Terpenoids have shown their bioactivity from antimicrobial to anticancer cases due to the presence of complex carbon skeletons and enzymatic transformations. Alkaloids with a nitrogen atom in a heterocyclic ring system exhibit potent pharmacological actions. Certain types of alkaloids also exert analgesic and anti‐inflammatory activities. Abundantly existing in fruits and vegetables, polyphonous act as vital antioxidants and anti‐inflammatory compounds for human health. Peptides and proteins that are naturally derived give an unexplored potential for targeting specific cellular pathways with high affinity and selectivity. Biosynthesis of natural products follows complex enzymatic pathways and genetic mechanisms within living organisms. Elucidation of these pathways provides insights not only into their biological function but also into biotechnological production and modification strategies for their sustain ability. Natural products represent very valuable leads in drug discovery, as has been unmistakably shown by compounds such as paclitaxel and artemisinin, which revolutionized the treatment of cancer and malaria, respectively. Further, challenges in supply sustain ability underline their ethical use and the preservation of biodiversity.
How to cite this article:
Parinita Tripathy and Sanyogita Shahi. AI‐Powered Mining of Nature's Chemical Library: Unveiling the Therapeutic Potential of Natural Products.
DOI: https://doi.org/10.36478/10.36478/makrjp.2024.3.32.37
URL: https://www.makhillpublications.co/view-article/1815-9362/10.36478/makrjp.2024.3.32.37