Research Journal of Medical Sciences
ISSN: Online 1993-6095ISSN: Print 1815-9346
Abstract
Thyroid hormones are essential regulators of carbohydrate metabolism, and their imbalance may disproportionately affect individuals with type 2 diabetes mellitus (T2DM). This study aimed to assess the profile of thyroid function among T2DM patients attending a tertiary care hospital in Hazaribagh, with the goal of identifying potential hormonal disturbances that could influence diabetic management. A total of 100 patients diagnosed with T2DM were selected from various clinical departments‐Medicine, Obstetrics & Gynecology, and Surgery‐at SBMC ,Hazaribagh. Participants were enrolled regardless of age or gender, and informal consent was obtained prior to inclusion. Fasting and postprandial blood glucose levels were determined using the Glucose Oxidase‐Peroxidase (GOD‐POD) method. Serum levels of triiodothyronine (T3), thyroxine (T4), and thyroid‐stimulating hormone (TSH) were evaluated using the Enzyme‐Linked Immunosorbent Assay (ELISA) technique. Additional data were collected on socio‐demographic variables, duration of diabetes, and anthropometric measurements. Waisthip ratio (WHR) was computed, and statistical analyses‐including means, standard deviations, and chi‐square tests—were performed to compare findings across groups. Of the 100 T2DM patients analyzed, a majority exhibited normal thyroid function. However, approximately one‐fifth showed subclinical abnormalities, such as euthyroid sick syndrome, subclinical hyperthyroidism, and subclinical hypothyroidism. The WHR was notably higher among those with diabetes. No participants showed signs of overt thyroid dysfunction. A mild upward trend in TSH levels was observed with longer diabetes duration, though this was not statistically significant. This study highlights the importance of evaluating thyroid function in patients with diabetes, even in the absence of overt symptoms. Identifying subclinical thyroid issues could support better glycemic control and help mitigate the risk of long‐term complications.
How to cite this article:
Rajiv Kumar Mahli, Mahto Hemanti Raghu and Pushpendra Narety. Evaluation of Thyroid Function Tests in Patients with Diabetes Mellitus: A Hospital‐Based Study.
DOI: https://doi.org/10.36478/makrjms.2025.5.28.33
URL: https://www.makhillpublications.co/view-article/1815-9346/makrjms.2025.5.28.33