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Research Journal of Medical Sciences

ISSN: Online 1993-6095
ISSN: Print 1815-9346
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Determinants of COVID‐19 Vaccine Acceptance and Disease Outcomes Among Home Isolated Patients: A Descriptive Study from South India

Devika Pandurang Jeeragyal, Korimerla Deepika, Kiran Velukuri, Hema Sree Lakshmi Guddeti, Chandana Sai Kodali and Sanjana Poladi
Page: 92-99 | Received 15 Mar 2025, Published online: 28 May 2025

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https://doi.org/10.36478/makrjms.2025.4.92.99

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Abstract

COVID‐19 has presented unprecedented challenges to global health systems. Vaccination remains the most effective strategy to reduce disease transmission, severity and mortality. However, vaccine acceptance and outcomes vary across populations. This study aimed to assess the vaccination status, determinants of vaccine acceptance, disease severity, recovery timelines and awareness levels among COVID‐19 positive individuals under home isolation in Chittoor, Andhra Pradesh. A descriptive follow‐up study was conducted between June and December 2022 at the Government Hospital, Chittoor. Adult patients diagnosed with COVID‐19 and advised home isolation were interviewed using a structured questionnaire. Data on vaccination status, clinical outcomes, awareness levels and perceived barriers to vaccination were collected via telephone. Descriptive statistics and logistic regression were used for analysis. Out of 504 participants, 72.8% were vaccinated and 57.5% had received two doses. Family vaccination coverage was also high (80%). Most patients (65.7%) experienced mild illness, while only 4.2% developed severe symptoms. Symptoms requiring medical attention were reported by 22.6%, but only 20.6% were shifted to hospital care. Recovery to full health was delayed in many cases, with 27% taking over two weeks. Vaccine hesitancy was low (3.2%), primarily due to fear of adverse effects and lack of awareness. Awareness regarding when, where, and whom to contact for vaccination exceeded 92% and 96.8% expressed willingness to motivate family members to get vaccinated. The findings highlight high vaccine uptake, strong community awareness and low vaccine hesitancy among COVID‐19 patients in home isolation. Vaccination was associated with milder illness and fewer hospital admissions. However, delayed recovery in a subset of patients and the presence of minimal hesitancy underscore the need for continued health education and post‐COVID care strategies. Strengthening public trust and ensuring equitable vaccine access remain essential to enhance pandemic response and preparedness.

How to cite this article:

Devika Pandurang Jeeragyal, Korimerla Deepika, Kiran Velukuri, Hema Sree Lakshmi Guddeti, Chandana Sai Kodali and Sanjana Poladi. Determinants of COVID‐19 Vaccine Acceptance and Disease Outcomes Among Home Isolated Patients: A Descriptive Study from South India.
DOI: https://doi.org/10.36478/makrjms.2025.4.92.99
URL: https://www.makhillpublications.co/view-article/1815-9346/makrjms.2025.4.92.99