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Research Journal of Medical Sciences

ISSN: Online 1993-6095
ISSN: Print 1815-9346
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Prevalence of Subclinical Thyroid Dysfunction in Reproductive-Age Women Presenting with Abnormal Uterine Bleeding: A Cross-Sectional Study

L. Bhuvaneswari and Pranadeep Reddy Inukollu
Page: 977-981 | Received 20 Oct 2024, Published online: 30 Dec 2024

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Abstract

Abnormal Uterine Bleeding (AUB) is a frequent gynecological complaint among reproductive-age women, with multifactorial etiology. While structural and hormonal causes are well recognized, thyroid dysfunctionparticularly in its subclinical form is increasingly being acknowledged as a contributing factor. Subclinical thyroid dysfunction may present without overt symptoms yet cause significant menstrual irregularities, including menorrhagia and oligomenorrhea. To determine the prevalence of subclinical thyroid dysfunction in reproductive-age women presenting with AUB and to correlate bleeding patterns with thyroid status. This cross-sectional study was conducted in the Department of Obstetrics and Gynecology at a tertiary care center, involving 170 women aged 18-45 years presenting with AUB. Detailed clinical evaluation and thyroid function tests (FT3, FT4 and TSH) were performed. Based on TSH levels with normal FT3 and FT4, patients were categorized as having subclinical hypothyroidism or subclinical hyperthyroidism. Out of 170 women, 23 (13.5%) had subclinical hypothyroidism, while 12 (7.1%) had subclinical hyperthyroidism. Menorrhagia was the most common bleeding pattern among those with subclinical hypothyroidism (43.6%), whereas oligomenorrhea was predominant in subclinical hyperthyroidism (75%). A significant number of women with AUB were found to have underlying thyroid dysfunction, emphasizing the importance of early screening. Subclinical thyroid dysfunction is a common, often overlooked cause of abnormal uterine bleeding in reproductive-age women. Routine thyroid function screening in AUB cases can facilitate early diagnosis, appropriate treatment and potentially prevent unnecessary surgical interventions.


How to cite this article:

L. Bhuvaneswari and Pranadeep Reddy Inukollu. Prevalence of Subclinical Thyroid Dysfunction in Reproductive-Age Women Presenting with Abnormal Uterine Bleeding: A Cross-Sectional Study.
DOI: https://doi.org/10.36478/makrjms.2024.12.977.981
URL: https://www.makhillpublications.co/view-article/1815-9346/makrjms.2024.12.977.981