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Research Journal of Medical Sciences

ISSN: Online 1993-6095
ISSN: Print 1815-9346
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Study of Outcome and Response of Hypofractionated Radiotherapy with Concurrent Cisplatin for Treatment of Stage II to IVA Head and Neck Cancer

Akhilesh Sahu, S.K. Azad, Pradeep Kumar Chandrakar, Umesh Dewangan, Vivek Choudhary, Manjula Beck, Rajeev Ratan Jain, Rahul Swaroop Singh and Divya Fransis
Page: 41-46 | Received 20 Feb 2024, Published online: 13 Apr 2024

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https://doi.org/10.36478/10.59218/makrjms.2024.6.41.46

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Abstract

The term “head and neck cancer” refers to cancers of the upper aerodigestive tract, including the lips, oral cavity, oropharynx, sinonasal cavities, nasopharynx, larynx, hypopharynx and salivary glands. to assess the response of hypofractionated radiotherapy with concurrent cisplatin for treatment of stage II to IVa head and neck cancer. The present prospective study was conducted in department of Radiotherapy, Pt. JNM medical college and Regional cancer center (RCC) of Dr. BRAM Hospital Raipur. This thesis was approved by ethical and scientific committee Pt. JNM medical college Raipur. Duration of study during July 2018‐ September 2019, Maximum number of patients are of oral cavity 36.59% followed by oropharynx 29.27%. It is due to people used to keep tobacco related products in mouth. Most patients presented with locally advance disease of stage IVA 58.54% and with early stage II 12.2%. it is due to in Chhattisgarh state patients came with locally advanced stage. It is due to illiteracy, poverty, lack of awareness, lack of health facility. In our study treatment should be completed within 1 week from estimated total duration (39 days) percentage are 41.4%, Rest of 58.6% patients delayed their treatment 39 days+2weeks. It mainly due to radiation‐related toxicities other reasons are distance of the treatment facility from home, age of the patient, advance stage , illiteracy and particular disease sites. In our study we observe response at 6 weeks, 3 months and 6 months. In 6 months‐there is complete response in 36.6% of cases, partial response in 39%, stable disease in 12.2% and progressive disease in 4.8% cases. It is due to 58.4% cases have presented to us with stage IVA and they not response completely and tend to progress even after treatment.

How to cite this article:

Akhilesh Sahu, S.K. Azad, Pradeep Kumar Chandrakar, Umesh Dewangan, Vivek Choudhary, Manjula Beck, Rajeev Ratan Jain, Rahul Swaroop Singh and Divya Fransis. Study of Outcome and Response of Hypofractionated Radiotherapy with Concurrent Cisplatin for Treatment of Stage II to IVA Head and Neck Cancer.
DOI: https://doi.org/10.36478/10.59218/makrjms.2024.6.41.46
URL: https://www.makhillpublications.co/view-article/1815-9346/10.59218/makrjms.2024.6.41.46