Research Journal of Medical Sciences
ISSN: Online 1993-6095ISSN: Print 1815-9346
Abstract
Levobupivacaine has a safety margin of 1.3, which means toxic effects are not seen until the concentration rises by 30%. The concentration necessary to produce cardiac and neurotoxicity is higher for levobupivacaine than for racemic bupivacaine. There are three case reports of successful resuscitation after inadvertent intravenous injection. A prospective randomized comparative study was conducted after obtaining the approval of institutional ethical committee. Data was collected from patients posted for lower abdominal surgeries in Department of anaesthesiology, pain and critical care. 60 patients were enrolled in this study, 30 in each group with inclusion and exclusion criteria. In our study hypotension was rerecorded in 4 patients (13%) from group B and 1 patient (3.3%) from group L with the p value of 0.021, which was statistically significant. Bradycardia was noted in 3 patients (10%) from group B and 1patient (3.3%) from group L with the p value of 0.053, which was not significant.
How to cite this article:
T.K. Haridadeeswaran, R. Thanuja, P.S. Kalesh, C. Lakshmi and C.G.S. Prasad. Intrathecal Levobupivacaine Versus Bupivacaine in Lower Abdominal Surgeries: Hemodynamic Changes.
DOI: https://doi.org/10.36478/10.59218/makrjms.2024.6.266.270
URL: https://www.makhillpublications.co/view-article/1815-9346/10.59218/makrjms.2024.6.266.270