Research Journal of Medical Sciences
ISSN: Online 1993-6095ISSN: Print 1815-9346
Abstract
Biofilms pose a number of clinical challenges to diseases involving uncultivable species, chronic, inflammation, impaired wound healing, recalcitrance to host immune defense mechanisms. Also, rapidly acquired antimicrobial resistance and the spread of infectous emboli. Regardless of the sophistications of the implant all medical devices are susceptible to microbial colonization and infection. Catheter associated infections due to microbial colonization and biofilm formation has gained more attention, increasing the incidence of nosocomial infections as a result of catheter use. The present study was carried out in the Department of Microbiology, to look for the biofilm forming ability of the organisms causing catheter related infection. Samples analyzed were intravascular catheters, Foley’s catheters, blood and urine samples. Samples were processed as per standard protocol and methods. A total of 106 catheter samples obtained from 105 patients were studied. Of the 106 catheter cultures, 11 isolates were coagulase negative staphylococci which were all 100% biofilm producers. All were 100% resistant to Ampicillin, 91.6% sensitive to Vancomyan and 100% sensitive to Linezolid. Out of 12 gram negative isolates, 11 were biofilm producers, which were 100% resistant to Ampicillin and Amoxycillin‐clavulanic acid, 100% sensitive to Imipenem. Therefore, it is necessary to detect the biofilm production in catheter‐related infections as they lead to persistent infections, show high antimicrobial resistance and are difficult to eradicate.
How to cite this article:
H. Kavitha, Pooja Mansabdar, B. Amrutha Kumari and K.R. Shobha Medegar. Catheter Related Infection: Biofilm Forming Capacity of Micro Organisms.
DOI: https://doi.org/10.36478/10.59218/makrjms.2024.6.250.254
URL: https://www.makhillpublications.co/view-article/1815-9346/10.59218/makrjms.2024.6.250.254