Research Journal of Medical Sciences
ISSN: Online 1993-6095ISSN: Print 1815-9346
Abstract
High plasma glucose that is first detected during pregnancy is known as gestational diabetes mellitus (GDM). Globally, GDM prevalence has been estimated to affect 7% of pregnancies; in India, this prevalence varies from 6-9% in rural areas to 12-21% in urban areas. To evaluate the effectiveness of CBG (Capillary Blood Glucose) as compared to venous plasma glucose after an oral glucose load of 75gms of glucose for diagnosis of GDM. This prospective observational, institution-based study was carried out from May 2020 to Oct 2021 at the ESI-PGIMSR, ESIC Medical College, JOKA, Kolkata, at the OPD/Ward of the Department of Obstetrics and Gynecology between 24 and 28 weeks of gestation. By WHO criteria (same cut off), Total GDM diagnosed 22 (among 22, GDM diagnosed by CBG 19-True Positive and GDM not diagnosed by CBG 3) and by same cut off Total GDM diagnosed by CBG is 25 (among 25,True Positive is 19 and 6 are diagnosed by CBG but not by WHO). Sensitivity of CBG = 86.36% (True Positive/Disease Positive), Specificity of CBG = 95.31% (True Negative/Disease Negative), PPV (Positive Predictive Value) of CBG = 78.45% NPV (Negative Predictive Value) of CBG = 97.25% Accuracy-94%. In Fisher’s exact test P-Value <0.0001 (P-value<0.05), Statistically significant i.e., CBG (same cut off like WHO) can be used as Diagnostic tool for GDM diagnosis like VPG (WHO criteria). In added cut off, Sensitivity of CBG = 77.27% (True Positive/Disease Positive), Specificity of CBG = 96.88% (True Negative/Disease Negative), PPV (Positive Predictive Value) of CBG = 80.75%,NPV (Negative Predictive Value) of CBG = 96.17%, Accuracy-94.03%,In Fisher’s exact test P-Value <0.00001 (P-value<0.05), Statistically significant i.e., CBG (Added cut off) can be used as Diagnostic tool for GDM diagnosis like VPG (WHO criteria). We concluded that the study indicates that the CBG method of screening of pregnant women can be a helpful tool in a nation like India, particularly in rural areas lacking access to laboratory facilities. However, more extensive research of this kind is needed to determine the precise CBG cutoff value for the diagnosis of GDM in pregnant mothers.
How to cite this article:
Surajit Adak. Comparison Between Capillary Blood Glucose and Venous Plasma Glucose after 75 g of Oral Glucose Tolerance Test for Diagnosis of Gestational Diabetes Mellitus.
DOI: https://doi.org/10.36478/10.59218/makrjms.2024.6.210.216
URL: https://www.makhillpublications.co/view-article/1815-9346/10.59218/makrjms.2024.6.210.216