Research Journal of Medical Sciences
ISSN: Online 1993-6095ISSN: Print 1815-9346
Abstract
Chronic kidney disease (CKD) is intricately linked to dyslipidemia, characterized by elevated triglycerides and decreased HDL concentration, while LDL levels typically remain relatively normal. This dyslipidemia profile poses a significant risk factor for coronary heart disease, highlighting the importance of managing lipid abnormalities in CKD patients. Recognizing distinct lipid patterns across different renal disorders is crucial for effective intervention and management strategies. The present study is a analytical observational study conducted in the Department of General Medicine at a tertiary care hospital asrams eluru. The duration of the study was six months, from January 2023, to June 2023.The study compared lipid profiles between chronic kidney disease (CKD) patients undergoing conservative treatment and hemodialysis. While total cholesterol (TC) levels did not significantly differ between the two groups, triglyceride (TG) levels were notably higher in the hemodialysis group. HDL cholesterol (HDLc), LDL cholesterol (LDL), VLDL cholesterol (VLDL) and the HDL/Total Cholesterol ratio showed no significant differences between treatment groups. These findings suggest that while treatment type may not significantly impact TC, LDL, VLDL, HDLc, or patients undergoing hemodialysis. Chronic kidney disease (CKD) patients exhibit elevated triglycerides and VLDL, alongside reduced HDL levels and HDL/TC ratio, heightening cardiovascular risk. HDL reduction and HDL/TC ratio serve as predictive indicators for coronary artery disease in CKD patients. Managing hyperlipidemia in CKD is crucial, as it accelerates renal failure progression and predisposes to atherosclerosis.
How to cite this article:
R. Praveen Kumar, N. Raghavaram, G. Raghavendra Rao, Yenduri Ramakrishna and R. Siddeswari. A Analytical Study on the Variations of Lipid Profile in Chronic Kidney Disease.
DOI: https://doi.org/10.36478/10.59218/makrjms.2024.6.191.195
URL: https://www.makhillpublications.co/view-article/1815-9346/10.59218/makrjms.2024.6.191.195