Research Journal of Medical Sciences
ISSN: Online 1993-6095ISSN: Print 1815-9346
Abstract
Lichen planus is a chronic, inflammatory skin disorder that can also affect mucous membranes, hair and nails. Despite being a relatively common dermatological condition, its exact etiology and epidemiology remain the subject of ongoing research. To study the epidemiological and clinicohistopathological pattern in Lichen planus. A retrospective analysis of medical records was conducted in a dermatology clinic over a five‐year period. Data from patients diagnosed with Lichen planus were collected and analyzed. Demographic information, clinical characteristics, including skin and mucosal involvement, nail and hair manifestations and comorbidities, were documented. The prevalence of Lichen planus was calculated based on the total number of dermatology clinic visits during the study period. A total of 100 patients with Lichen planus were included in the study. The majority of patients were adults, with a median age of 45 years. Lichen planus exhibited a slight male predominance. The most common clinical presentation was cutaneous Lichen planus with the most frequent morphology being papular and violaceous lesions. Histopathological presentations include Hyperkeratosis (74%), Hypergranulosis (76%), Acanthosis (73%), Basal cell degeneration (75%), Melanin Incontinence (63%) and Civatte bodies (14%). 100 patients of Lichen planus after histopathological confirmation were tested for detection of HCV antibodies, Hbs antigen and HIV antibodies by HCVTRIDOT, HEPACARD and HIV –TRIDOT respectively. This clinicoepidemiological study sheds light on the clinical characteristics and prevalence of Lichen planus in a dermatological clinic setting. There is no significant relationship between Lichen planus and Hepatitis B, C and HIV virus. It may be suggested that viral serology (HBsAg, HCV, HIV) may not be necessary in routine screening for Lichen planus.
How to cite this article:
B. Nikhil, B. Pavithra and M. Lohita. Clinico‐Epidemiological Study of Lichen Planus.
DOI: https://doi.org/10.36478/10.59218/makrjms.2024.6.147.151
URL: https://www.makhillpublications.co/view-article/1815-9346/10.59218/makrjms.2024.6.147.151