C reactive protein (CRP) is regarded as an acute phase reactant which is found to be increased in various infections and inflammation. It is produced in liver mainly in response to interleukin 6. It is found to be increased in acute infections of various organs. It also indicates low grade inflammation in human body. In recent pandemic by Severe acute respiratory syndrome corona virus 2 (SARS CoV 2) various biochemical, hematological and inflammatory biomarkers played vital role in diagnosis, prognosis and treatment of Covid‐19. Due to its complex nature of presentation, initially researchers explored various biomarkers which could prove useful in better management of the patients. CRP which rises early in Covid 19 infection was one of the most important markers helping in stratification and management of patients. In various studies, CRP was shown to be a severity and mortality indicator in Covid‐19 patients. Hence, in this review, we aim to discuss role of CRP in severe and critical patients of Covid‐19 infection.
Kedar Balwant Joshi, Roshni Khundrakpam and Parveen Kavathekar. C Reactive Protein and SARS‐CoV‐2 Infection Severity A Systematic Review.
DOI: https://doi.org/10.36478/10.59218/makrjms.2024.5.58.64
URL: https://www.makhillpublications.co/view-article/1815-9346/10.59218/makrjms.2024.5.58.64