Research Journal of Medical Sciences
ISSN: Online 1993-6095ISSN: Print 1815-9346
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Pattern of Utilization of Anti‐Hypertensive Drugs Among Patients With Chronic Kidney Disease Undergoing Maintenance Haemodialysis at a Tertiary Care Hospital of Southern Part of West Bengal
Soumyadeep Mahapatra, Trisha Banik and Sabyasachi Majee
Page: 568-573 | Received 05 Feb 2024, Published online: 26 Mar 2024
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Abstract
In the present world, Chronic Kidney Disease (CKD) has become a major threat to patients worldwide due to several associated co‐morbidities, which renders the use of polypharmacy in these patients. Antihypertensive drugs are prescribed for managing high blood pressure, which is the leading cause of mortality in patients with CKD undergoing maintenance hemodialysis. However, very little information is available regarding proper treatment and drug utilization patterns of hypertension in CKD patients in India. The objective of our study is to study the utilization pattern of antihypertensives in patients suffering from chronic kidney disease undergoing maintenance hemodialysis in a tertiary care teaching hospital. This is an observational prospective hospital‐based study conducted at Jagannath Gupta Institute of Medical Sciences and Hospital, Budge Budge, South 24 Parganas, West Bengal from 1st May to 31st October 2020. The data was collected from the prescriptions and bedhead tickets of the patients regarding patient details, antihypertensive and other drugs utilized during treatment, relevant vital parameters and biochemical reports. The data was compiled in Microsoft Excel and the result was expressed as Mean ± Standard deviation. Based on the calculated sample size, a total of 100 prescriptions were analyzed. The study population had male predominance (72%), with a mean age of 48.37±17.41 years. Most of the patients belonged to the age group 41‐60 years (71%) followed by those within the age group 61‐80 years (21%). All the patients in the study were hypertensive (100). Most of the patients were suffering from Stage 5 (eGFR<5ml/min/1.73m2) chronic kidney disease (68). All the patients were being prescribed Anti‐hypertensive drugs, Haematinics, Proton pump inhibitors, Antibiotics, anti‐emetics and 25% Dextrose. Among the anti‐hypertensives, Calcium channel blockers (82%) were most commonly used, followed by Beta‐blockers (60%), Loop diuretics (55%) and Central sympatholytics (46%). Blood pressure control (<140/90mm Hg) was achieved in 17% of patients, whereas 83% of patients had BP >140/90mm Hg after 6 months of treatment given in the prescriptions analyzed. The pattern of prescription of anti‐hypertensive drugs in patients suffering from hypertension associated with advanced stages of Chronic Kidney Disease (undergoing maintenance dialysis) requires rationality during prescribing. Both positive and negative effects of such drugs should be kept in mind before prescription.
How to cite this article:
Soumyadeep Mahapatra, Trisha Banik and Sabyasachi Majee. Pattern of Utilization of Anti‐Hypertensive Drugs Among Patients With Chronic Kidney Disease Undergoing Maintenance Haemodialysis at a Tertiary Care Hospital of Southern Part of West Bengal.
DOI: https://doi.org/10.36478/10.59218/makrjms.2024.5.568.573
URL: https://www.makhillpublications.co/view-article/1815-9346/10.59218/makrjms.2024.5.568.573