Abnormal uterine bleeding (AUB) is a broad term that describes irregularities in the menstrual cycle involving frequency, regularity, duration and volume of flow outside of pregnancy. Present study was aimed to correlate two dimensional ultrasonography and histopathology in patients with abnormal uterine bleeding at a tertiary hospital. Present study was hospital based prospective, analytical study, conducted in perimenopausal and postmenopausal women with abnormal uterine bleeding, underwent operative management. All patients underwent clinical examination, transvaginal sonography and detailed histological study. Among 50 patients, majority of the patients (68%) were in the age group of 40‐45 years and most common presentation was Menorrhagia (44%) followed by Metrorrhagia (18%), Menometrorrhagia (14%), Polymenorrhagia (14%) and Post‐menopausal bleeding (10%). The most common ultrasonography finding was Fibroid uterus (46%) followed by Bulky uterus (28%), Thickened endometrium (12%), Adenomyosis (10%), Endometrial polyp (2%). The histopathology finding of myometrium was fibroid in 23 (46%) patients, adenomyosis in 9 (18%) patients and normal myometrium in 18 (36%) patients. Histopathology of endometrium showed hyperplastic endometrium in 28 (56%) cases, secretory in 9 (18%) cases, proliferative in 7 (14%) cases, atrophic and carcinoma endometrium in 2 (4%) cases. There was 1 (2%) case each of endometrial polyp and inflammatory endometrium. The Sensitivity, Specificity, Positive Predictive Value (PPV) and Negative Predictive Value (NPV) in the detection of fibroid were 88.94%, 88.71, 89.64% and 91.14% respectively. The Sensitivity, Specificity, PPV and NPV in the detection of adenomyosis were 49.47%, 96.88%, 97.14% and 88.57% respectively. The study provides a concrete evidence that ultrasonography has good diagnosis of fibroid in patients with abnormal uterine bleeding. The combination of procedure viz: ultrasonography and histopathology can aid in a better diagnosis rather than a single procedure.
Kinjal Parikh, Richa Singh and Ashvini Deshmukh. Prospective and Analytical Study to Correlate Two Dimensional Ultrasonography and Histopathology in Patients with Abnormal Uterine Bleeding.
DOI: https://doi.org/10.36478/10.59218/makrjms.2024.5.516.521
URL: https://www.makhillpublications.co/view-article/1815-9346/10.59218/makrjms.2024.5.516.521