files/journal/2022-09-03_18-51-40-000000_599.png

Research Journal of Medical Sciences

ISSN: Online 1993-6095
ISSN: Print 1815-9346
About US
Editors
Issues
Pages
Indexed in
134
Views
20
Downloads

A Prospective Randomized Control Study Comparing the Efficacy of Intra‐Articular Platelet Rich Plasma Versus Intra‐Articular Steroid in Primary Osteoarthritis of Knee

Nagabhushan Patil, H. Devendra, Suresh Uliveppa Kadli and Shivakumar Kerakkanavar
Page: 388-391 | Received 13 Jan 2024, Published online: 15 Feb 2024

Download Citation
https://doi.org/10.36478/10.59218/makrjms.2024.5.388.391

Full Text Reference XML File PDF File

Abstract

Osteoarthritis (OA) of the knee is one of the main causes of musculoskeletal disability. It is clinically heterogeneous and the processes that causes deterioration are still poorly understood. Current research efforts are focused on the identification of key biochemical pathways that can be targeted therapeutically through biological intervention and the testing of protein biotherapeutics for restoring the metabolic balance within the joint. This is a hospital based prospective randomized controlled trail. 80 patients are choosen and randomly divided into two groups of 40 each. Group 1 received intra articular injection of platelet rich plasma into the knee. Group 2 received intra articular steroid. The patients are subjected to a standardized injection protocol and are assessed on variables such as pain, stiffness and physical function using WOMAC scale and for pain, using visual analog scale at pre injection, 6 wks. post injection, 3 months and 6 months post injection. The study showed a significant decrease in global WOMAC score for group 1 patient, which was also consistent throughout the study period. Visual analog score showed a significant decrease in mean for group 1 patients, which denoted a change in patients perception of pain from intense, dreadful, horrible pain to mild annoying pain. Group 2 showed a marginal dip in VAS showing insignificant change in pain.

How to cite this article:

Nagabhushan Patil, H. Devendra, Suresh Uliveppa Kadli and Shivakumar Kerakkanavar. A Prospective Randomized Control Study Comparing the Efficacy of Intra‐Articular Platelet Rich Plasma Versus Intra‐Articular Steroid in Primary Osteoarthritis of Knee.
DOI: https://doi.org/10.36478/10.59218/makrjms.2024.5.388.391
URL: https://www.makhillpublications.co/view-article/1815-9346/10.59218/makrjms.2024.5.388.391