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Research Journal of Medical Sciences

ISSN: Online 1993-6095
ISSN: Print 1815-9346
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Rare Presentation of Uremic Frost in a Young Adult with Advanced Renal Failure

Ravi Panwar, Pulkit Jain, Mahesh Pratap Ahirwar, Sanjay Bhoraskar and Ashish Sharma
Page: 380-383 | Received 31 Dec 2023, Published online: 18 Feb 2024

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Abstract

Uremic frost is an uncommon occurrence that can arise as a result of chronic renal failure. Here, we offer a case of a 32‐year‐old male who presented for the first time with the lesions. The most prominent physical observation was the presence of a white powdery frost covering the entire body, particularly concentrated on the face and limbs. Frosting can occur with less severe forms of uremia, but typically occurs when the blood urea nitrogen concentration exceeds 200 mg/dL. The impairment of the small blood vessels and the structures responsible for hair follicles and oil glands, observed in chronic renal illness, may explain the accumulation of elevated quantities of urea on the skin surface. The primary objective of uremic frost treatment is to rectify the root cause of uremia and other critical medical conditions. Uremic frost is a rare manifestation of chronic kidney disease. Here, we present a case of a 32‐year‐old boy who presented for the first time with the lesions. The most striking physical finding was whitish powdery frost all over his body, especially the face and limbs. Uremic frost generally occurs at blood urea nitrogen of more than 200 mg/dL, although it may arise with less severe uremia. Damage of cutaneous microvasculature and pilosebaceous units, as seen in chronic kidney disease, could account for the high levels of urea deposited outside the skin. Treatment of uremic frost is mainly aimed at correcting the underlying cause of uremia and other life‐threatening conditions.


How to cite this article:

Ravi Panwar, Pulkit Jain, Mahesh Pratap Ahirwar, Sanjay Bhoraskar and Ashish Sharma. Rare Presentation of Uremic Frost in a Young Adult with Advanced Renal Failure.
DOI: https://doi.org/10.36478/10.59218/makrjms.2024.5.380.383
URL: https://www.makhillpublications.co/view-article/1815-9346/10.59218/makrjms.2024.5.380.383