Research Journal of Medical Sciences
ISSN: Online 1993-6095ISSN: Print 1815-9346
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A Study to Assess the Prevalence of Sexual Dysfunction in Psychiatric Patients Taking Antipsychotic Medications: A Prospective Observational Study
Bhavinkumar N. Kadavala, Mark Andrew. S, Rajesh. D and Prashant M. Parmar
Page: 336-340 | Received 15 Jan 2024, Published online: 14 Feb 2024
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Abstract
Sexual dysfunction (SD) is a prevalent concern in individuals with mood disorders and psychotic conditions, with reported rates of 30%‐80% in women and 45%‐80% in men. Antipsychotic medications, used for managing psychosis, are associated with substantial impairment of sexual function. This study addresses a gap in the literature regarding the prevalence and types of SD in individuals receiving oral antipsychotic treatment in Gujarat, India. A prospective observational study conducted at a tertiary care teaching hospital in Gujarat from January 2021 to December 2023 included 200 participants on antipsychotic medication. Inclusion criteria involved age over 18, specific psychiatric diagnoses, and active engagement in sexual activity. Exclusion criteria comprised certain medications and medical conditions affecting sexual function. A locally adapted questionnaire and the PRSexDQ assessed clinical and demographic data and SD, respectively. Data analysis utilized Graphed version 8.Demographic analysis revealed diverse characteristics among the 200 participants, predominantly diagnosed with schizophrenia. Respiration was the most prescribed antipsychotic. Sexual dysfunction prevalence was 56.5%, with a notable gender difference‐ 66.14% in males and 39.73% in females. Different forms of SD were categorized, emphasizing simultaneous dysfunction in desire, arousal, and orgasm as most prevalent at 56.64%.This study underscores a significant prevalence of SD among individuals on oral antipsychotic treatment in Gujarat, with higher rates in males. Respiration was frequently prescribed, aligning with a meta‐analysis on varied antipsychotic impacts on sexual function. Consistent impairment in desire/libido, influenced by dopamine blockade and elevated prolactin levels, highlights the complex interplay of Antipsychotic, SD and underlying psychotic conditions. Further research, incorporating randomized designs and dose‐related investigations, is crucial for a more comprehensive understanding of these relationships.
How to cite this article:
Bhavinkumar N. Kadavala, Mark Andrew. S, Rajesh. D and Prashant M. Parmar. A Study to Assess the Prevalence of Sexual Dysfunction in Psychiatric Patients Taking Antipsychotic Medications: A Prospective Observational Study.
DOI: https://doi.org/10.36478/10.59218/makrjms.2024.5.336.340
URL: https://www.makhillpublications.co/view-article/1815-9346/10.59218/makrjms.2024.5.336.340