Research Journal of Medical Sciences
ISSN: Online 1993-6095ISSN: Print 1815-9346
Abstract
Purpose: To evaluate the RNFL thickness in diabetic patients with and without Diabetic retinopathy without macular edema. Study design: A cross sectional, non interventional observation study. A total of 124 subjects were consecutively recruited for the study. Thus, a total of 124 eyes of 124 subjects were included in the analysis and were classified into two groups. The association if any of Retinal nerve fibre layer (RNFL) thickness with diabetic retinopathy and the also the possibility of RNFL thickness changes being a precursor to diabetic retinal changes was evaluated in this study. Peripapillary RNFL thickness was measured using spectral domain OCT Optovue (U.S.A) (software version 11.1;) and reported as an overall mean and by quadrants, Macular scan was performed, to exclude macular edema. On comparison between DM with retinopathy and DM without retinopathy, the global RNFL thickness showed significant difference with mean±SD of 94.15±10.1and 98.5±16.9 respectively with p value of 0.06. The superior quadrant RNFL thickness showed significant difference with mean±SD of 115.19±13.9 and 124.77± 8.1 respectively with p value of 0.001 and the temporal RNFL thickness showed highly significant difference with mean±SD of 66.71±13.52and 71.56±11.85 respectively with p value of 0.14. There was significant reduction in RNFL thickness in especially in superior and temporal quadrant in patients with diabetic retinopathy as compared to diabetic patients without retinopathy.
How to cite this article:
Nilesh Gaddewar and Bharat Bharvesh. Comparison of Retinal Nerve Fibre Layer Thickness in Diabetic Patient with and Without Diabetic Retinopathy.
DOI: https://doi.org/10.36478/10.59218/makrjms.2024.5.272.277
URL: https://www.makhillpublications.co/view-article/1815-9346/10.59218/makrjms.2024.5.272.277