Research Journal of Medical Sciences
ISSN: Online 1993-6095ISSN: Print 1815-9346
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Abstract
Avascular necrosis (AVN) of the femoral head is a debilitating condition commonly observed in patients with sickle cell disease (SCD). This crosssectional study aims to evaluate the prevalence and identify risk factors of AVN among SCD patients. A cohort of 200 SCD patients was selected for this study. Data collection involved reviewing medical records, conducting physical examinations, and analyzing imaging results. Participants ranged in age from 15‐60 years, with a diverse representation of genders and SCD severity levels. Statistical analysis was performed to identify potential risk factors associated with the development of AVN. The prevalence of AVN in the study population was found to be significantly high, with a notable percentage of patients demonstrating early signs of femoral head necrosis. Key risk factors identified included age, severity of SCD, history of steroid use and frequency of vaso‐occlusive crises. The study also uncovered a correlation between the duration of SCD and the onset of AVN. The study confirms a high prevalence of AVN in SCD patients and identifies several significant risk factors. These findings underscore the need for early screening and targeted interventions in the SCD population to prevent or delay the onset of AVN. Further research is recommended to explore the pathophysiological mechanisms underlying AVN in SCD and to develop more effective management strategies.
How to cite this article:
Rajkumar Indrasen Suryawanshi, Sanjay Gavit, Abhijit Chintamani Mahajan and S. Aravind. Avascular Necrosis of the Femoral Head in Sickle Cell Disease Patients: A Cross‐Sectional Analysis.
DOI: https://doi.org/10.36478/10.59218/makrjms.2024.5.115.119
URL: https://www.makhillpublications.co/view-article/1815-9346/10.59218/makrjms.2024.5.115.119