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Research Journal of Medical Sciences

ISSN: Online 1993-6095
ISSN: Print 1815-9346
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A Comparison of Scoring Systems and Amplitude‐Integrated Electroencephalography in Neonates with Hypoxic Ischemic Encephalopathy to Predict Adverse Neurological Outcome A Prospective Cohort Study

Mohit Sharma, S. Manikumar, S. Ramya and N. Muthukumaran
Page: 154-159 | Received 25 Nov 2023, Published online: 04 Jan 2024

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https://doi.org/10.36478/10.59218/makrjms.2024.3.154.159

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Abstract

Early identification of HIE in newborns is very crucial for the decision to start Hypothermia and subsequent outcome. AEEG has been proved to be a useful tool in predicting Neuro developmental outcome and to select infants for cooling as it is easy to perform bedside and gives continuous real time monitoring. Objective of present study is Comparison of clinical scoring systems (with and without aEEG) and aEEG to assess the severity of HIE based on adverse neurological outcome before discharge. Forty one babies who had clinical signs and symptoms of HIE required resuscitation at birth (PPV or more) and admitted to NICU who fulfil the inclusion criteria are enrolled into the study. Each baby enrolled into the study is assigned clinical scoring within 6 hrs and before the initiation of TH or usage of AED for seizure episodes. Scoring will be done at 1‐3 and 6 hours and the maximum score will be taken for the analysis . AEEG will be done for all the babies being recruited for the study and quantified as normal or abnormal ( before the initiation of TH ). The sensitivity and Negative Predictive Value (NPV) for abnormal scores in all scoring systems was 100%. The specificity was highest for normal NICHD score. Positive Predictive Value (PPV) was highest for abnormal Thompson and NE‐RS Score. We found that Scoring systems used in the study and aEEG both useful predictor for short‐term neurologic outcome in preterm infants. Amplitude‐integrated electroencephalography, preterm infant, neurological outcomes, Sarnat score, Thompson score, NICHD score, SIBEN score, NE‐RS.

How to cite this article:

Mohit Sharma, S. Manikumar, S. Ramya and N. Muthukumaran. A Comparison of Scoring Systems and Amplitude‐Integrated Electroencephalography in Neonates with Hypoxic Ischemic Encephalopathy to Predict Adverse Neurological Outcome A Prospective Cohort Study.
DOI: https://doi.org/10.36478/10.59218/makrjms.2024.3.154.159
URL: https://www.makhillpublications.co/view-article/1815-9346/10.59218/makrjms.2024.3.154.159